Peptides & Peptide Synthesis Products
Rink Amide AM Resin

Rink Amide AM Resin

Rink Amide MBHA Resin

Catalog No: 52002
4-(2′,4′-Dimethoxyphenyl-Fmocaminomethyl) -phenoxyacetamidomethylbenzhydryl amine resin
100-200 mesh, 0.3-0.8 mMol/g

Rink Amide MBHA Resin

This resin is less acid sensitive than Rink Amide resin because the benzhydrylamine linker is joined to the support through an electron-withdrawing acetamido spacer [1]. Normally the product is detached from the resin using 95% TFA in DCM plus scavengers as required by the composition of the substrate [1, 2]. It is also useful for preparing peptides. Boussard, Cyrille et al. has reported that synthesis of tri- and tetra- and pentapeptides were performed via a solid phase synthesis methodology using a Rink Amide MBHA resin [3].

[1] Bernatowicz, M. S., Daniel, S. B., Koster, H., Tetrahedron Lett., 1989, 30, 4645

[2] M. Lebl, et al., J. Comb. Chem., 1999, 1, 474

[3] Boussard, Cyrille, et al., European Journal of Medicinal Chemistry, 2002, 37(11), pp, 883-890

More Information
Catalog Number 52002
Synonym 4-(2′,4′-Dimethoxyphenyl-Fmocaminomethyl) -phenoxyacetamidomethylbenzhydryl amine resin
Mesh Size 100-200
Substitution (mMol/g) 0.3-0.8
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